Goodness-of-Fit for Length-Biased Survival Data with Right-Censoring

Goodness-of-Fit for Length-Biased Survival Data with Right-Censoring

Détails

Titre: Goodness-of-Fit for Length-Biased Survival Data with Right-Censoring
Auteur: Younger, Jaime
Résumé: Cross-sectional surveys are often used in epidemiological studies to identify subjects with a disease. When estimating the survival function from onset of disease, this sampling mechanism introduces bias, which must be accounted for. If the onset times of the disease are assumed to be coming from a stationary Poisson process, this bias, which is caused by the sampling of prevalent rather than incident cases, is termed length-bias. A one-sample Kolomogorov-Smirnov type of goodness-of-fit test for right-censored length-biased data is proposed and investigated with Weibull, log-normal and log-logistic models. Algorithms detailing how to efficiently generate right-censored length-biased survival data of these parametric forms are given. Simulation is employed to assess the effects of sample size and censoring on the power of the test. Finally, the test is used to evaluate the goodness-of-fit using length-biased survival data of patients with dementia from the Canadian Study of Health and Aging.
Date: 2012
URI: http://hdl.handle.net/10393/20670
Superviseur: Bergeron, Pierre-Jérôme
Faculté: Sciences / Science
Degré: MSc

Fichier(s) constituant ce document :

Fichier(s) Taille Format
Younger_Jaime_2012_thesis.pdf 1.600Mb application/pdf Voir/Ouvrir

Cet article est disponible dans les collections suivantes

Détails


Nos coordonnées

Pavillon Morisset (carte)
65, rue Université
Ottawa ON Canada
K1N 6N5

Tél. 613-562-5800 (4563)
Fax 613-562-5195

ruor@uottawa.ca